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Review Article

Acute lymphoblastic leukemia (ALL) is a relatively rare cancer affecting 1.7 cases per 100,000 people annually in the United States, with a slightly higher incidence in males than females.
Nausea and vomiting are common side effects of anticancer agents and can have significant negative impact on patients’ quality of life and on their ability to tolerate and adhere to cancer treatment. “Despite advances in the prevention and management of chemotherapy-induced nausea and vomiting (CINV), these side effects remain among the most distressing for patients,” Rao and Faso noted in their review of CINV prevention and management.
Immune checkpoint inhibitors, including programmed-cell death (PD)-1 and cytotoxic T-lymphocyte–associated protein (CTLA)-4 inhibitors, have proved to be effective in treating many cancers, but in rare cases, have been reported to cause fatal and life-threatening immune-mediated adverse events (AEs).
The American Cancer Society estimates that approximately 63,990 patients will be diagnosed with renal cancer in the United States in 2017. In addition, approximately 14,400 patients are projected to die in 2017 from renal cancer. Renal cancer is one of the 10 most common malignancies in men and women in the United States. In recent years, the incidence of this disease has been on the rise.
Prostate cancer is the second leading cause of cancer-related mortality, and accounts for 10% of cancer-related deaths in American men. It is estimated that 1 in 9 men will have prostate cancer during their lifetime, and an estimated 161,363 new cases and 26,730 prostate cancer–related deaths are expected in the United States in 2017.
Lung cancer is the leading cause of cancer-related death in men and women in the United States.
The chronic lymphocytic leukemia (CLL) development landscape is one of the most dynamic areas in oncology clinical research. During the writing of this manuscript, there were new approvals made, and guidelines were updated.

Non-Hodgkin lymphoma (NHL) represents a heterogeneous group of predominantly mature malignancies originating from B lymphocytes, T lymphocytes, or natural killer cells.

Chronic lymphocytic leukemia (CLL) is a disease that predominantly occurs in older adults; the median age at diagnosis is 71 years. Therefore, the CLL population typically has age-related comorbidities.
Lack of sufficient vitamin B12 intake is often associated with the development of vitamin B12 deficiency anemia, which is a medical condition characterized by a low red blood cell count and vitamin B12.
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