Original Research

Ákos Juhász, PharmD, and colleagues, suggest that the use of a closed-system drug-transfer device to reduce the high levels of cytotoxic drugs would reduce the levels of contamination found in hospital pharmacies.

The approved uses of oncology treatments are generally based on the cancer site, cancer stage, disease characteristics, and line of therapy. Concerns have been raised about the appropriateness of off-label use of drugs in oncology, particularly with novel, high-cost agents.

In a review of studies examining tobacco use among patients diagnosed with cancer, the rate of patients who were smokers at the time of their cancer diagnosis ranged from 46% to 75%. Among the patients who were smokers at diagnosis, the reviewers estimated that up to 58% of patients continued to smoke after initiating cancer therapy.

The World Health Organization’s pain ladder for cancer recommends opioids for the treatment of moderate-to-severe pain in patients with cancer, and is a mainstay of cancer pain therapy.

Drug containers are defined in USP 797 based on the type of the container and the environment in which the container is opened. Vials are further divided into 2 categories: single-dose or multiple-dose.

Oral chemotherapeutic agents have been available for many years, and were traditionally cytotoxic drugs, such as cyclophosphamide, methotrexate, and mercaptopurine. In recent years, oral anticancer medications are being used more often in many types of cancer.
It is well-known that patients with acute myeloid leukemia (AML) who receive induction and reinduction chemotherapy and any patients undergoing hematopoietic stem-cell transplant (HSCT) are at high risk for infections and prolonged hospital stays. Intensive chemotherapy regimens used in these settings cause patients to be neutropenic for prolonged durations.
Pain is one of the most feared symptoms of cancer, with uncontrolled pain being the most frequently reported symptom in hospitalized patients with cancer. As cancer stage progresses, the pain intensity and incidence increase, with cancer pain reported in 62% to 86% of patients with advanced disease.
Pharmacists are becoming increasingly involved in cancer care. This raises a vital question: How aware are pharmacy students of the expanding roles and opportunities in oncology pharmacy?
The paradigm of oncology practice has changed significantly in recent years with the rapid emergence and use of oral chemotherapy agents.
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