JHOP - March 2016 Vol 6, No 1
Neutropenia Recovery Linked to Filgrastim Initiation Timing After Autologous Hematopoietic Stem-Cell Transplantation
Marissa Janusek, PharmD, Lisa DiGrazia, PharmD, BCPS, BCOP, Kathryn Schultz, PharmD, BCPS, BCOP, Laura Geswein, PharmD, BCPS, Christopher W. Crank, PharmD, BCPS, MS, AQ-ID, Henry C. Fung, MD, FRCPE
High doses of chemotherapy in patients who undergo autologous hematopoietic stem-cell transplantation (HSCT) can result in delayed or incomplete engraftment. Granulocyte colony-stimulating factors are used to decrease the time to engraftment; however, the optimal timing of filgrastim initiation following autologous HSCT is unknown.
Hypercalcemia is defined as a condition in which the serum calcium level is >10.5 mg/dL (the upper limit of normal) or the ionized calcium level exceeds 5.6 mg/dL. The consequences of abnormally high serum calcium can range from asymptomatic to life-threatening.
Treatment of chronic myeloid leukemia (CML) with imatinib and more recent therapeutic agents has brought a drastic change in the course of this malignancy. Some patients never experience disease progression, and, therefore, may expect long-term survival with such treatment.
- Aprepitant Effective in Preventing Chemotherapy-Induced Nausea and Vomiting in Children
- Bevacizumab for Advanced Lung Cancer Does Not Increase Risk for Hospitalization or Unexpected Toxicity
- Daratumumab, an Anti-CD38 Monoclonal Antibody, Effective Treatment Option for Patients with Relapsed and/or Refractory Multiple Myeloma
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