With the increasing incidence of cancers in the HIV-infected population, a better understanding of the clinical effects of the coadministration of chemotherapy and antiretroviral medications needs to be known.
Mucositis is a significant adverse effect of chemotherapy that often leads to treatment delays or to dose reductions.
In the majority of patients with follicular lymphoma (FL), chemotherapy results in initial high rates of remission, but the disease relapses in many patients.
Crizotinib, an inhibitor of the anaplastic lymphoma kinase (ALK) gene, has shown significant response rates in patients with advanced non–small-cell lung cancer (NSCLC) and the ALK rearrangement.
The neoadjuvant treatment of breast cancer usually involves cytotoxic chemotherapy, not hormonal therapy. This study is one of the first to look at hormonal therapy as a neoadjuvant strategy in this setting.

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