Case Report

In patients with renal-cell carcinoma who require co-administration of everolimus with strong CYP3A4 inducers, the everolimus dose may be increased in 5-mg increments, from 10 mg to 20 mg daily, without monitoring of serum trough levels. This recommendation, however, is based on predictive models and not on clinical data.2,3

Hematology oncology pharmacists should be aware of this rare and potentially devastating complication of temozolomide therapy.

To our knowledge, cases of successful treatment of chronic myeloid leukemia (CML) with low-dose nilotinib (Tasigna) have not been reported. The following case represents our experience with a patient with CML who achieved good response to nilotinib therapy.
To our knowledge, cases of successful treatment of chronic myeloid leukemia (CML) with low-dose nilotinib (Tasigna) have not been reported. The following case represents our experience with a patient with CML who achieved good response to nilotinib therapy.

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