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What are some treatment options for elderly patients with chronic lymphocytic leukemia?

Q: Is it safe for women at risk for breast cancer–related lymphedema to lift weights?

The systemic amyloidoses are a group of complex diseases caused by tissue deposition of misfolded proteins that results in progressive organ damage.1 The incidence of immunoglobulin light chain (AL) amyloidosis (also referred to as primary amyloidosis) is approximately one-tenth that of multiple myeloma,1 a more common cancer of the bone marrow plasma cells.

Although there is no straightforward answer to this question, the current recommended daily allowances for adults—600 IU for children and adults, and 800 IU for those older than 70 years— are probably too low.1,2 To provide a little background, vitamin D should be considered a prohormone rather than a vitamin (a substance humans need in small amounts and usually cannot synthesize).3 Animals convert 7-hydrocholesterol to calciferol (D3) in the dermis via a photochemical reaction with ultraviolet B (UVB) sunlight.

Chronic lymphocytic leukemia (CLL) is a neoplastic disease characterized by the accumulation of monoclonal lymphocytes in blood, bone marrow, and lymphoid tissue.1 It is the most common form of leukemia in adults worldwide, with prevalence increasing with age.

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